BP Neural Networks and Its Application in Lung Cancer Intelligent Diagnosis System

The learning algorithm of networks is discussed. The programming example of 3 layer BP networks is given with Visual C++6.0 program langue. Based on this model, a lung cancer intelligent diagnosis system is successfully implemented. Furthermore, the paper introduces network's structure design, preferencesand the source of stylebookdatum in factual applications. The ameliorative arithmetic is applied to the study of networks and BP dynamic evolving process is designed. The experiments indicatecell images are recognized and classified by the trained neural network. The study illustrates the system has feasibility and clinical value in lung cancer diagnosis.     

Effects of naringenin on PI3K/AKT signaling pathway and endoplasmic reticulum stress and its related apoptotic pathways in rats with myocardial ischemia/reperfusion injury

AIM To observe the effect of naringenin on cardiac injury in ischemia/reperfusion （I/R） rats, and to explore whether the role of naringenin is involved in PI3K/AKT signaling pathway and endoplasmic reticulum stress and its related apoptotic pathways. METHODS SD rats （n=48） were randomly divided into sham operation （sham） group, model （I/R） group, naringenin treatment （NAR） group and naringenin+LY294002 （NL） group. Myocardial I/R injury model was prepared by ligation of left anterior descending coronary artery of rats for 30 min followed by reperfusion for 120 min. After reperfusion, the serum levels of cardiac troponin I （cTnI） was measured by ELISA. HE staining, TTC staining and TUNEL staining were used to detect the myocardial histopathological changes, myocardial infarction area and myocardial cell apoptotic rate. The mRNA levels of endoplasmic reticulum stress-related indicators glucose-regulated protein 78 （GRP78）, C/EBP homologous protein （CHOP） and caspase-12 were detected by RT-qPCR. The protein levels of cleaved caspase-3, GRP78, CHOP, caspase-12, p-PI3K and p-AKT were determined by Western blot. RESULTS Compared with I/R group, the serum content of cTnI, myocardial pathological damage, myocardial infarction area and myocardial cell apoptotic rate were significantly reduced （P<0.05）, the protein levels of cleaved caspase-3, GRP78, CHOP and caspase-12 were decreased （P<0.05）, and the protein levels of p-PI3K and p-AKT were increased in NAR group （P<0.05）. LY294002 attenuated the protective effect of naringenin to some extent. CONCLUSION Naringenin reduces myocardial I/R injury in rats possibly by activating PI3K/AKT signaling pathway and subsequently regulating endoplasmic reticulum stress and its related apoptotic pathways.     

倒春寒危害软籽石榴树的温度及受害情况研究

以突尼斯软籽石榴为试材,在倒春寒发生前2 d开始持续监测石榴树冠层温度,倒春寒结束后调查石榴树受倒春寒危害的临界低温及寒害症状。结果表明,软籽石榴树春季生长期间,岭地、沟地和台地石榴树冠层温度降至1.4℃、-0.1℃、2.3℃,气象预报低温低于6.4℃时,石榴树芽和新梢发生低温寒害,芽尖焦枯发黑,芽体展叶受阻;新梢幼叶扭曲畸形,叶缘焦枯。     

Injuries associated with the cartilages of the foot

There is a growing body of evidence that uniaxial or biaxial ossification of the cartilages of the foot should not be discounted as irrelevant in a lame horse, especially if extensive. Potential causes of pain and lameness include primary injury of an ossified cartilage and/or the ipsilateral aspect of the distal phalanx, injury of the chondrocoronal or chondrosesamoidean ligaments and desmopathy of the collateral ligaments of the distal interphalangeal joint.     

核桃树冻害发生原因及冻害预防对策

核桃已成为新疆叶城县农民家庭经济收入的重要来源。但核桃树低温冻害造成其巨大经济损失。现就核桃树冻害发生原因、预防对策及补救措施进行总结。